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SA国际传媒

Hot as a hare, mad as a hatter: Cracking the toxidrome code

Before you grab the naloxone or reach for the benzos, hit play on this toxidrome masterclass

In this episode of the Inside EMS podcast, hosts Chris Cebollero and Kelly Grayson dig deep into one of EMS鈥檚 most overlooked (and often forgotten) topics 鈥 toxidromes. You might remember the word from paramedic class, but today鈥檚 street calls demand more than a vague memory. With patients taking everything from grandma鈥檚 Ativan to street-made speed, understanding toxidromes is crucial for making quick, accurate clinical calls.

The crew breaks down the five major toxidromes every medic should know: anticholinergic, cholinergic, opioid, sympathomimetic and sedative-hypnotic. From classic mnemonics like 鈥渕ad as a hatter鈥 to real-life stories of fire ant poisonings, this episode serves up practical knowledge with EMS-grade humor.

Chris and Kelly cover telltale signs (sweaty vs. dry skin, pinpoint vs. dilated pupils), treatment pearls of wisdom (easy on that naloxone, folks), and the real-world complications of polypharmacy. Plus, they touch on lesser-known players like serotonin syndrome and hallucinogens.

This one鈥檚 a refresher you didn鈥檛 know you needed 鈥 but you鈥檒l be grateful when you respond to your next overdose call.

Memorable quotes

  • 鈥淎ntidotes are overrated. Supportive care will take care of most of the toxidromes out there.鈥 鈥 Kelly Grayson
  • 鈥淚f they鈥檙e pleasantly stuporous but breathing effectively, it鈥檚 not an overdose. It鈥檚 just a dose.鈥 鈥 Kelly Grayson
  • 鈥淣arcan is not a punishment, it鈥檚 a treatment. You don鈥檛 slam it, you bump it just a little bit, just enough to get them breathing again.鈥 鈥 Kelly Grayson

RATE & REVIEW
Catch a new episode of the Inside EMS podcast every Friday on鈥,鈥, 鈥,鈥,鈥, and鈥. Enjoying the show? Please take a moment to鈥. Contact the Inside EMS team at鈥theshow@ems1.com鈥痶o share ideas, suggestions and feedback, or let us know if you鈥檇 like to join us as a guest.

SA国际传媒 uses generative AI to create some content that is edited and fact-checked by our editors.

The Inside EMS podcast is a regular expert discussion of hot topics, clinical issues, operational and leadership lessons for EMTs, paramedics and chiefs